I don't know about the ITEM brand. I have used slotted extrusions from 80/20 and found them satisfactory. They have complete systems in several modules in both metric and american dimensions. Pick one or the other; you will go nuts if you end up with a mixed inventory.
Beware of generic aluminum profiles. The extrusion industry standard allowable tolerances for camber and twist are huge.
Your specification is still incomplete; you haven't revealed whether the table is stationary or must travel, what loads are applied by the weight of the workpiece and by the operations being performed on the workpiece, or how much table deflection is allowable when said loads are applied, the positioning accuracy and resolution required of the cnc controller, the trajectory error allowed of the moving parts, and more.
If you 'support the table from below', what supports the supports?
Yes, you could make a grid of t-slotted bars, modular if you like. You need a leveled surface to set the supports on, or a way to level the bars when you place them.
How much time can you allow to set up a given workpiece? How long does the operation take? How many workpieces will you make? In what time period?
Of course, there's always the 'zero-mass' solution: Drop the workpiece on the floor in a pool of molten wax, wait for the wax to harden, and work on it where it is. Given the right cnc controller, you wouldn't even need a level floor; you could just touch off three points on the blank and call that a reference plane.
That's just an example; I can come up with more, and more bizarre, ideas, but you'll need to reveal just a bit more about what, exactly, you're trying to do.
And how much money you've got. Then we'll have a good laugh, and work from there.
-Mike-