Is that an admonition or a layout name??? ;-)
Short locos and impossibly lage radii!
Yes, that sort of thing can be done, in fact has to be done for my sort of radii! Built an outside cylindered 4-4-0 with second and fourth axles rigid and the driving axle flangeless. That worked very well. DJH's 2-12-0 with second driving axle and fifth driving axle rigid, third and fourth on a narrow bogie. It goes around 360mm radii without problems and minimal overhangs.
Some people are never satisfied ;-)))))
Greg.P.