In the early 90's I dreamed up an alien sci-fi technology that had never invented transistors, instead they made repairable integrated tube circuits for their spacecraft by soldering the elements onto a printed substrate in a large chamber ventilated to space. When the gain decreased they repainted all the cathodes with Caesium or Radium in an Argon glove box.
I mentioned the idea to an engineer at work (Mitre) who told me about ongoing research in that direction.
-jsw