My career never included the use of the spotting drills, only center drills, so I don't know that I can address your question. My hunch would be they would work fine for drilling to depth, but it's also entirely possible that the point,which is rather fragile, might not stand up nearly as well as the chisel point of the conventional jobbers twist drill. Could be some of the CNC guys that use them routinely could address the issue, having used them in their setups. Good question, by the way.
Harold