If making such a device, there is a distinct possibility of the main frame being twisted, misaligned, or bent in any of the three axes, despite the care that we would obviously take in its manufacture
It seems to me that with the power of computers that we all now have at our disposal, that it should be a relatively straightforward matter to employ some form of correction map, together with the calibration procedures to set up the map, so that whatever we mill will come out the correct shape independently of the geometry of the mill.
The integrated printer/scanners that are now available do this, so it should be feasible for us.
What do the market leaders such as Mach3 do in this respect?