Sure, air powered with wet paper on them. Grit depends on what coat your on.
Going over a dry vehicle to break the gloss on the paint and provide tooth for a sealer - 220 Going over the final primer coat as prep for the color coat - 400 then a follow up wiping with wax and grease remover.
Final sanding before a buffing - 1200 ON A HAND BLOCK!
BUT you will want to practice with the D/A before you use it a lot. There are a lot of paint jobs that look like an ocean due to rocking the D/A while using it. You want to hold it FLAT on most surfaces use the edge in grooves and such.
Keep in mind that after every use you will want to wipe down with W?G remover. This is due to the air supply having oil in it.
I also HIGHLY recommend that if your doing ANY painting with a gun that you get a GOOD water separator and a different hose to feed the gun. Mark it and cap it off after each use. That way you have a clean air line to use. NEVER use it for tools, just gun use.